1. Automatic Nucleic Acid Extractor

Nucleic acid extraction instrument is an instrument that automatically completes the extraction of sample nucleic acid by using the matching nucleic acid extraction reagent . It can replace the original complex manual operation, the instrument automatically completes the processing of cells or tissues, and analyzes and extracts the target DNA/RNA. At present, the extraction principles of nucleic acid extractors on the market are mainly divided into two types: magnetic bead method and membrane adsorption method, among which magnetic bead method occupies the mainstream position in the market.

Nucleic acid extraction by magnetic bead method is to lyse cells by cell lysate, and the nucleic acid molecules freed from the cells are specifically adsorbed to the surface of magnetic particles, while impurities such as proteins are not adsorbed and remain in the solution. After a certain time of reaction, under the action of a magnetic field, the magnetic particles are separated from the liquid, and the particles (ie, the magnetic bead-DNA mixture) are recovered, and then eluted with the eluent to obtain pure DNA.

Membrane adsorption method: according to the principle of membrane-specific adsorption to achieve nucleic acid separation

2. Introduction of common imported nucleic acid extraction instrument brands:

1. American Promega

Promega is an innovative reagent and technical support for the life sciences. The company's more than 2,000 products advance the knowledge discovery of scientists around the world in genomics, proteomics, cellular analysis, molecular diagnostics and identification. Founded in 1978, Promega is headquartered in Madison, USA, with branches in 15 countries and more than 50 global distributors.

2. Germany QIAGE

The German biotech company QIAGEN was founded in 1986. The existing market value is 800 million US dollars, and the number of employees worldwide is more than 1,500, distributed in 10 countries. A global leader in the development of products and technologies for the isolation and purification of nucleic acids (DNA and RNA).

   Qiagen offers more than 500 categories of products, including various reagents, consumables and automated purification workstations. These products are used for sample collection, stabilization, separation, purification and detection of nucleic acid or protein. It has also been widely used.

3. Roche, Switzerland

Founded in 1896 and headquartered in Basel, Switzerland, Roche is one of the leading R&D-based, innovation-driven health companies in the fields of pharmaceuticals and diagnostics.

The MagNA Pure LC 2.0 System from Roche can isolate and purify DNA, RNA and mRNA (PCR grade) from various biological samples (whole blood, leukocytes, peripheral blood, monocytes, cultured cells, tissues, paraffin-embedded tissue sections, etc.). purity).