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How to understand molecular diagnostic reagents?

2022-06-15 17:02:26
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Molecular diagnosis reagent raw materials Molecular diagnosis mainly refers to the detection of disease-related structural proteins, enzymes, antigen antibodies and various immune active molecules, as well as the genes encoding these molecules. From a technical point of view, molecular diagnosis can be understood as molecular biological diagnosis. Because whether it is protein detection or gene detection, the methods used, such as enzyme treatment, electrophoresis, molecular hybridization, PCR amplification, DNA sequencing, etc., are all molecular biology techniques.

Molecular diagnostic reagent raw materials

Molecular Diagnosis: A technology that uses molecular biology methods to detect changes in the structure or expression level of genetic material in patients to make a diagnosis, which is called molecular diagnosis. Molecular diagnosis is the main method for predictive diagnosis, which can be used for the diagnosis of individual genetic diseases and prenatal diagnosis. Materials for molecular diagnostics include DNA, RNA, and proteins. Countries around the world attach great importance to the development of molecular diagnostic technology, and gene chips will become the mainstream of the development of new-generation molecular diagnostic reagents. Gene chip is the crystallization of the combination of molecular biology, microelectronics, computer and other disciplines. The gene chip has the function of being able to detect multiple targets at the same time, which is fast and effective. Therefore, gene chips have become the main development direction of a new generation of molecular diagnostic reagents. 

Molecular diagnosis relies on molecular biology technology and has become a frontier subject of clinical medicine, playing an increasingly important role in the diagnosis and treatment of genetic diseases, tumors and other diseases. Molecular diagnosis mainly detects nucleic acids, including DNA and RNA, using the principle of nucleic acid hybridization, and primers and probes are commonly used tools. Current clinical detection-based technologies and methods include mutation/variation detection technology, DNA sequencing technology, biochip technology, PCR technology, fluorescence in situ hybridization (FISH), capillary electrophoresis and mass spectrometry.



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